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(116) to clarify the causality between the gut microbiota and musculoskeletal disorders restricted the scope of orthopedic pathologies to six musculoskeletal diseases that may be highly associated with the gutbone axis: osteoporosis, fracture, myasthenia gravis, low back pain (LBP), rheumatoid arthritis (RA), and ankylosing spondylitis

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Mice were treated iLN (Supplemental Fig

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