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Although diabetes is widely accepted as one of the major risk factors for cardiovascular disease, the cardiovascular safety of antidiabetic drugs has been questioned due to the finding that intensive glycemic control by antidiabetic medications may result in an unexpected increase in cardiovascular death under certain circumstances [6]

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Patients who have pre-existing moderate or worse NPDR at baseline need to be seen more frequently to monitor for EWDR

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A Danish nationwide cohort study also reported a lower risk of corticosteroid use and hospitalization in IBD patients with DM2 undergoing GLP-1 RAs rather than other antidiabetic treatments (98)

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