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and can lead to or exacerbate many other significant physical and mental health challenges, including type 2 diabetes, heart disease and depression

Arterburn LM, Coleman CD, Kiel J, et al

Originally developed for managing blood sugar, these treatments, including well-known options like semaglutide and tirzepatide, have a powerful effect on the hormones that regulate appetite and satiety

GNC offers HMB, a metabolite of the amino acid leucine with many human clinical studies to support its use, which helps users maintain muscle and creatine can improve the effectiveness of strength training for lean muscle building and maintenance

10.1038/282260a0 43