glp-1 gip gcg Potential of a glucagon‐like peptide‐1 receptor/glucose‐dependent insulinotropic polypeptide receptor/glucagon receptor triagonist for the treatment of obesity and type 2 diabetes - Araki - 2022 - Journal of Diabetes Investigation Neurotrophic and neuroprotective effects of
Description
Schechter, G
Side Effects Weve already noted how safe bariatric surgery is compared with other procedures
GLP-1 inhibits pancreatic alpha-cells, thus inhibiting glucagon secretion, although the exact mechanism by which it acts on alpha-cells is not fully understood
On a cellular level, the polarization of macrophages has been stimulated by this molecule, shifting them from the inflammatory M1 phenotype to the anti-inflammatory M2 phenotype, which plays a vital role in tissue regeneration as well in reducing inflammation, as they produce cytokines like IL-10 and TGF-[5]
They were also more likely to achieve clinically meaningful milestones like losing 5% or 10% of their starting weight
Effects of exenatide on kidney function, adverse events, and clinical end points of kidney disease in type 2 diabetes
