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New England J Med 385(6):503515 Funding Karan Chhabra is supported by KL2 TR001446 from the National Center for Advancing Translational Sciences, National Institutes of Health

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The cardiovascular phenomenon of endothelial dysfunction involves a series of structural and functional abnormalities, including abnormal secretory capacity and properties of the endothelium and impaired vascular tone, as well as an impaired endothelial barrier function