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The decline is gradual

Longer-term prospective and randomized studies are needed to confirm the durability of weight loss, clarify differential metabolic effects, and evaluate long-term cardiovascular and hepatic outcomes in treatment-nave populations

Rotate through the Ozempic injection sites each week

Both Rybelsus and Ozempic contain the active ingredient semaglutide and work by mimicking a hormone called GLP-1, which increases insulin production and reduces appetite

Insufficient human clinical trials have led to a lack of data to determine a safe dose

Importantly, as liraglutide is the only currently approved GLP-1 RA therapy approved for children, this work will have broad impacts on a broad range of people