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Full ESSENCE trial results and Research Summary:

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This molecule is designed to explore potential mechanisms in regulating blood glucose, body weight, and energy metabolism through synergistic multi-pathway actions

Here, we investigated the role of three C-terminal serine doublets (Ser441/442, Ser444/445, Ser451/452) in the human receptor using site-directed mutagenesis in INS-1 832/3 -cells deleted for endogenous GLP-1R expression

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