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Cold constricts blood vessels and reduces bleeding into surrounding tissue
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this is not an approved prescribing schedule
This delayed transit can lead to constipation in 12-26% of patients, depending on dose and indication
doi: 10.1158/2159-8290.CD-17-0741 63 DonohueEThomasAMaurerNManisaliIZeisser-LabouebeMZismanNet al
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