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Chronic inflammation in the etiology of disease across the life span
Notable findings include: In the SURMOUNT-1 trial of tirzepatide for the treatment of obesity, secondary findings showed improvements in the GLP-1 treatment group in systolic blood pressure (-7.2mm Hg), diastolic blood pressure (-4.8mm Hg), triglycerides (-24.8mg/dl), fasting insulin (-42.9mIU liter), and total cholesterol (-4.8mg/dl)
Many lipedema patients struggle with weight management because of the distinctive fat deposition patterns
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Hepatic fat reduction, in particular, may not fully reverse immediately, giving the liver additional time to recover from years of steatotic damage
