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However, the drug did appear to cause higher rates of gastrointestinal side effects such as nausea and diarrhoea, particularly at the highest dosage
Due to the small sample size, we believe that this limited the ability to establish statistical significance when comparing change in HbA 1C concentration and weight between formulations and likely contributed to the unexpectedly large numerical HbA 1C concentration decrease seen in the oral semaglutide 14-mg group

That means youre less likely to get a sharp spike and crash in blood sugar

Tadross JA, le Roux CW

Diabetes Care 45 , 29912998 (2022)

& Van Gaal, L