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Description
Because GLP-1 slows gut motility, theres a risk of worsened constipation in IBS-C

A consistent A1C within your target range means the medication is working effectively

Unlike GLP-1RAs, DPP-4is have no significant impact on body weight due to the limited enhancement of GLP-1 activity [51,52,53]

The Bottom Line Forty million Americans taking GLP-1 drugs for weight loss, a meaningful decline in the national obesity rate, stabilizing diabetes diagnoses, and a new Medicare program offering $50 monthly access to Wegovy and Zepbound 2026 is shaping up as an inflection point for obesity treatment in the United States

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Patients also often notice temporary bouts of fatigue when starting the drug
