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Description
Glucagon-like peptide-1 (GLP-1) receptor agonists have been used extensively in the clinic and have an established safety profile in cardiovascular disease settings
This primarily appears to be due to clinical results since GLP-1s lower A1C, reduce weight, improve cardiovascular outcomes, and potentially many other benefits

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Moreover, our data reveal novel aspects of GLP-1 stimulated insulin secretion involving de novo gene expression.

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