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doi: 10.1210/clinem/dgaa285
It does not mean the compound "stopped working." It means it is clearing your system as intended
Natural product research, 29(23), 22562260
[DOI] [PMC free article] [PubMed] [Google Scholar] 231.Lu Y., Liu Y., Krumholz H.M
In the intervening time, it has dropped down to 36.4 percent, while diagnoses of diabetes are also stabilizing after rising for 15 years
The washout is shorter at the minimum recommended 20 to 25 days
