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A 2023 analysis of semaglutide users found that approximately 1520% experienced moderate gastrointestinal symptoms during the first 8 weeks, and adding an NSAID during this sensitive period increased symptom severity by 3040%

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This reflux-related irritation can feel like a sore throat but originates from the digestive tract rather than infection

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suggested that the duodenal mucosa could potentially release a hormone that acts as an excitant for internal pancreatic secretions [8]

Researchers found that people taking GLP-1 drugs were 66% more likely to be diagnosed with gastroparesis than those who were not