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95% confidence interval [CI] 0.140.74), parenteral nutrition needs (HR 0.28

But efficacy is only half the story

Trulicity is injected under the skin (subcutaneously) of your stomach (abdomen), thigh, or upper arm

While GLP-1 receptor agonists can aid weight loss by reducing appetite and increasing fullness and satiety, survodutide goes a step further by activating glucagon receptors, which are believed to help regulate metabolic functions in the liver

4 The role of GLP-1/GLP-R in related disease 4.1 Diabetes Diabetes mellitus is characterized by increased inflammation, reflecting innate immune control disorders, and studies have shown a local intestinal intraepithelial lymphocyte (IEL)-GLP-1 receptor (GLP-1R) signaling network that controls the mucosal immune response (43)

We were quite excited by the findings, as this study was the first to demonstrate a physiological role of GLP-1 in appetite control and energy intake in humans