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Muscle is metabolically active tissue, which means it burns calories even at rest

Among the GLP-1RAs, exenatide poses the highest risk since the kidneys eliminate it

Burke O, Sa B, Cespedes DA, Sechi A, Tosti A

A statin should be started, regardless of baseline lipid levels, for any patient with diabetes who has overt CVD

This likely reflects the glucagon receptor activation increasing sympathetic tone and thermogenesis, the same mechanism that drives the additional metabolic benefits
