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Start with: 'What is your experience prescribing semaglutide, and what outcomes have you seen in your patients?' This tells you whether your doctor is comfortable managing GLP-1 therapy and has realistic expectations

[2] Additionally, findings from SURPASS-1 and SURPASS-2 highlight the importance of gradual dose increases to improve patient adherence and reduce dropouts

However, despite these advances, many patients continue to face poor medium-term prognoses

How do they compare to true GLP-1 medications
Diabetes Obes Metab 20:22382245 Reigner BG, Williams PE, Patel IH, Steimer JL, Peck C, Van Brummelen P (1997) An evaluation of the integration of pharmacokinetic and pharmacodynamic principles in clinical drug development
