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Effects of pioglitazone in patients with type 2 diabetes with or without previous stroke: results from PROactive (PROspective pioglitAzone Clinical Trial In macroVascular Events 04)

Patients with a history of retinopathy should undergo ophthalmologic evaluation before initiating therapy and be monitored closely during treatment, as determined by the prescribing clinician
Tirzepatide received its first FDA approval in 2022
Studies show that patients who reach higher therapeutic doses (0.52.4 mg weekly for semaglutide) achieve greater weight loss and longer-lasting results than those who stop at lower doses

A., Naqvi, R

In monotherapy, when Metformin is not considered adequate due to intolerance or contraindications
