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The FDA advises against its use due to reports of severe side effects, including an elevated risk of liver failure

J Ethnopharmacol (2005) 97:2158

Exp Gerontol (2010) 45:2027

PMID 25475122

More recently, oral formulations of GLP-1 receptor agonists have been developed, with oral semaglutide (Rybelsus) becoming the first in this class to receive regulatory approval

Db/m mice were set as the Control group, and db/db mice were randomly divided into Model group, Low group and High group