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When combined, GIP/GLP-1 therapies offer an even stronger impact on insulin regulation and appetite management

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These substances contribute to insulin resistance, dyslipidemia, and systemic inflammationkey drivers of type 2 diabetes, cardiovascular disease, and metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as NAFLD)

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In them, patients taking the highest weekly dose (15 mg) of Zepbound lost 48 pounds on average, while those taking the lowest dose (5 mg) lost on average 34 pounds (compared to 7 pounds on placebo) over 72 weeks