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Description
When pharmacological intervention is indicated, NICE guidance presents orlistat as an option for adults meeting specific BMI criteria with comorbidities or higher BMI thresholds without comorbidities
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The frequency classification is generally similar across this medication class, suggesting that headache may be a class effect related to incretin-based mechanisms rather than specific to tirzepatide's dual GIP/GLP-1 action
While generally well-tolerated, some patients may experience nausea, vomiting, constipation, diarrhea, or headache
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