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Clinical indications and comorbidities play a primary role in medication selection
If cardiovascular health is what you think is important for deciding between these drug classes, I think our most recent study provides some strong evidence

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R.SivitsG.HagerT.AtanganL.et al (2020)

TREK-1 regulation by nitric oxide and cGMP-dependent protein kinase

There is increasing evidence that both EPA and DHA support insulin regulation and reduce the risk of developing T2DM
