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Spots corresponding to ThT-bound aggregates were selected by applying a threshold equal to the mean + 5 x S.D

Together, these mechanisms highlight the bidirectional interaction between gut and liver and support therapeutic strategies targeting microbiota composition and intestinal barrier integrity in MASLD

GPCRs are currently among the most extensively investigated drug targets in pharmaceutical industry (30-40% of actual drugs in the market)

Front Neurosci [Internet] Front Neurosci

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The benefits of these medications for glycaemic control and cardiovascular risk reduction generally outweigh the potential pancreatic risks in appropriately selected patients