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13 The median expected protection we determined for GLP-1 receptor agonistswhich exceeds 18 yearsis the highest yet reported for drug-device combinations

By improving metabolic regulation, moderating nutrient signaling, and reducing chronic inflammatory burden, these therapies may help alleviate physiological stress that contributes to age-related disease and functional decline

Therefore, whether lactate can promote fibroblast activation via NLRP3 inflammasome was investigated by exogenous lactate treatment and NLRP3 knockdown

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Fish oil supplementation and insulin sensitivity: a systematic review and meta-analysis

Understanding the broad mechanism of action is essential when considering whether GLP-1 medications might influence hormonal balance more generally, particularly given their increasing use in diverse patient populations including those with metabolic syndrome, polycystic ovary syndrome (PCOS), and obesity-related endocrine dysfunction