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Because human phenotyping studies have not demonstrated clear mechanisms as to how GLP-1 receptor agonists improve kidney outcomes, a reduction in kidney inflammation that is difficult to measure in humans remains a leading candidate mechanism

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Reference #18.9d0c0317.1784433397.ac7ba05c

J Clin Endocrinol Metab 1993;76:79-84.ArticlePubMed 45

Topamax side effects Common Topamax side effects include tingling sensations, dizziness, fatigue, and sometimes more severe issues like cognitive disturbances or mood changes
