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These studies refine our understanding of the relative importance of peripheral versus central GLP-1R activation for satiety and weight loss

2025 [cited 11 July 2025] Janumet 50 mg/1000 mg film-coated tablets- Patient Information Leaflet (PIL) - (emc) [Internet]

Diabetes - GLP-1 agonists should be primarily considered in patients with type 2 diabetes with suboptimal glycaemic control despite maximal tolerated dose of metformin (+/- other agents) especially where weight loss is desired and/or significant stroke risk is present

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Zhang Z, Yang X, Song YQ, Tu J
2024 [Google Scholar] 254.Hasan B., Thompson W.G., Almasri J., Wang Z., Lakis S., Prokop L.J., Hensrud D.D., Frie K.S., Wirtz M.J., Murad A.L., et al
