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Simultaneously, sympathetic nervous system activity measured by HR variability and the rate-pressure-product were also elevated, and increases in HR, systolic BP and sympathetic nervous system activity were still observed even with a concomitant L-NMMA-infusion [38]

The pattern of fat loss, the degree and distribution of skin laxity, and the quality of remaining subcutaneous tissue are often distinct

PLoS One 7:e32008

The mechanisms responsible for these effects are not entirely clear, but the slowing of gastric emptying may be the key driver
