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Longer-term use should only occur under clinical supervision
Initial reports of cases of PDAC began to emerge more than 10 years ago in relation to exenatide (Table 1) 32

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Semaglutide: Effectiveness and Side Effects Sunrise Weight Loss utilizes Semaglutide, a GLP-1 medication known for its weight-loss potential

Published phase 2 research reported that the most common adverse events in retatrutide groups were gastrointestinal, dose-related, and mostly mild to moderate in severity

GLP-1 weight loss drugs linked to small rise in chronic cough Most weight lost on GLP-1 drugs returns within a year after stopping Weight loss surgery outperforms GLP-1 drugs in real-world use The authors also note that cost, insurance limits and side effects are major reasons people stop in the first place, with cost and coverage being the main issue.
