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doi: 10.1016/j.ceb.2011.09.003 60 BarzilaiNCrandallJPKritchevskySBEspelandMA

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Frontiers in Human Neuroscience, 8

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Thus, in order to have GLP/GIP analogs with lasting effects, alterations of the peptides needed to be made in order to prevent their rapid metabolism by DPP-4 and oral administration could not be used

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Newer incretin-based therapies and considerations for pregnancy Emerging therapies that target multiple incretin pathways such as Retatrutide (a triple agonist targeting GLP-1, GIP and glucagon receptors) and Cagrisema (a dual agonist mimicking GLP-1 and amylin) will require thorough investigation for their safety and efficacy in pregnancy

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Checked bags may be exposed to extreme temperatures, which can damage medication or make it less effective

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possibly particularly for those with PCOS and/or insulin resistance

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