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Higher doses suppress appetite more

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& Tschop, M

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Common (may affect up to 1 in 10 people) low blood sugar (hypoglycaemia) when this medicine is used with oral diabetes medicine other than sulfonylurea or insulin being sick (vomiting) upset stomach or indigestion inflamed stomach (gastritis) the signs include stomach ache, feeling sick (nausea) or being sick (vomiting) reflux or heartburn also called gastro-esophageal reflux disease stomach pain bloating of the stomach constipation tiredness less appetite gas (flatulence) 5 increase of pancreatic enzymes (such as lipase and amylase) shown in blood tests

Most patients find that initial nausea and digestive changes subside within the first two to four weeks at each dose level