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The caveat: clinical doses in those trials were generally 10 grams or more per day

Published: March 12, 2026 Copyright: 2026 Xiang et al

Cell Physiol Biochem 53:865886 Juni RP, Kuster DWD, Goebel M, Helmes M, Musters RJP, van der Velden J, Koolwijk P, Paulus WJ, van Hinsbergh VWM (2019) Cardiac Microvascular Endothelial Enhancement of Cardiomyocyte Function Is Impaired by Inflammation and Restored by Empagliflozin

Second, a large percentage of patients had multiple reasons for discontinuation in their notes

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