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Insurers typically require documentation of inadequate glycemic control despite metformin therapy, contraindications to other agents, or presence of specific comorbidities that make GLP-1 therapy medically necessary
doi: 10.2165/11592810-000000000-00000 [DOI] [PubMed] [Google Scholar] 138

Meeting Protein, Calorie and Fiber Needs: GLP-1s may lower your appetite so much that it becomes difficult to eat enough

For example, people with lupus have a higher risk of developing conditions like type 2 diabetes and metabolic syndrome, both of which can make managing the disease more difficult

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