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Decreased exercise tolerance during treatment was linked with greater lean body mass loss in both groups, but to a greater extent in tirzepatide-treated patients

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Clinical research suggests that tirzepatide may produce greater average weight loss for some individuals, likely because it activates two metabolic hormone pathways instead of one

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Type 2 diabetes mellitus is a common comorbidity in dermatology patients, and understanding the multifactorial effects of these medications can help optimize treatment strategies, especially in patients with coexisting dermatologic and metabolic diseases.

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Sorli, C., Harashima, S

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