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Better yet, the risk continued to drop over time

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Todays market leaders include semaglutide (branded as Ozempic for diabetes and Wegovy for weight management) and tirzepatide (branded as Mounjaro for diabetes and Zepbound for weight management)

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Semaglutide increases feelings of fullness by slowing stomach emptying and activating satiety centers in the brain, which naturally shifts how much food feels satisfying

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Now, advocates fear that cutting coverage will undo years of progress

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In severe cases, dehydration or hypoglycemia (especially if used with certain drugs like insulin or sulfonylureas) can occur

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doi:10.1016/j.bcp.2020.114187 67

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