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Conclusions Consistent with clinical trials, real-world tirzepatide treatment was associated with greater 6-month weight reduction and more frequent achievement of weight-reduction targets and improvements in select cardiometabolic parameters than semaglutide among adults with obesity without diabetes

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Learn why 0.25 mg is the starting point, how it works, and its role in a safe, effective weight loss journey

Semaglutide works for many people, but approximately 15-30% of users experience minimal weight loss or hit a plateau

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