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The addition of GIP receptor agonism on top of dual GLP-1/glucagon activity provides synergistic metabolic effects includ
Furthermore, Novo Nordisk will have strengthened their market position by patenting the same drug (semaglutide) for different uses, e.g., semaglutide for use in the treatment of diabetes and separately for use in the treatment of weight loss (termed second medical use in Europe)
The kidney and heart protective effects of glucagon-like peptide 1 (GLP-1) receptor agonists are not fully explained by their metabolic effects
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