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doi: 10.2337/dc17-1956 [DOI] [PubMed] [Google Scholar] 58

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We observed a pronounced vehicle-corrected weight loss of 15.2% in the group treated with GLP-1MK-801 compared with 3.5% in the group treated with the parent GLP-1 analogue after 9 days of treatment, underscoring that the weight-lowering efficacy of the conjugate is intact in the absence of functional MC4R signalling (Fig