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Description
Importantly, this increase in insulin happens only when glucose levels rise (i.e., when the body needs insulin)
In some studies, these medications enabled: Faster achievement of technical operability Easier laparoscopic access Improved metabolic control Higher diabetes remission rates, especially in insulin-dependent patients 2

GLP-1 (glucagon-like peptide-1) is a naturally occurring metabolic hormone released by specialized intestinal cells in response to food intake

Consequently, on top of the beneficial effect of weight loss caused by GLP-1 analogues these drugs also cause a substantial reduction of the glycemic load (GL = carbohydrate intake X Glycemic index), which per se reduces hyperinsulinemia and causes weight loss [22], reduce diabetes risk [23], inflammation [24], and cardiovascular risk [25]

10.1001/jama.2021.1831 24 WildingJ

Ann Intern Med 150(9):604612