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Reeva Salkin, DNP, APN-BC, ANP-BC is a neurology specialist with Shore Physicians Group who treats patients age 18 and older

This review also summarizes our current understanding of the mechanisms by which GLP-1 affects bone metabolism

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Concurrently, GLP-1 stimulates the translocation of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) into the nucleus via the PKA/ERK signaling pathway, where Nrf2 induces transcription of genes for SOD, GPx, catalase, thioredoxin, and other antioxidant enzymes, further enhancing the cellular antioxidant defense system

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