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The gastrointestinal side effects may also prove more problematic for older adults, particularly those with existing digestive conditions or those taking multiple medications that interact with gut function

While peptide-based GLP-1 receptor agonists such as Exenatide, Liraglutide, Dulaglutide, and Semaglutide have demonstrated strong efficacy, there remains significant interest in developing next-generation therapies

It is not yet clear whether the Wegovy pill will be available on the NHS following UK approval

Proline dehydrogenase is a positive regulator of cell death in different kingdoms

2.3 Study outcome The primary endpoint of this study was the first occurrence of a composite outcome, including suicidal ideation or suicide attempts, after the index date