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A total of 32 adult patients with anti-exenatide antibodies in BYDUREON Trial 9 were tested for the presence of cross-reactive antibodies to GLP-1 and/or glucagon and no treatment-emergent cross-reactive antibodies were observed

1 Later, the American Association for the Study of Liver Diseases led the adoption of a new multisociety Delphi consensus in 2023, proposing metabolic dysfunction-associated steatotic liver disease (MASLD) as another replacement term for nonalcoholic fatty liver disease

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Several agents have shown cardiovascular outcome benefits in select populations, which guides therapy selection for people with existing atherosclerotic cardiovascular disease

2 Other possible side effects include acute cholelithiasis, hypersensitivity reactions, acute kidney injury secondary to undesirable GI side effects, and thrombocytopenia

According to findings published in the Journal of the American Medical Association, the prevalence of diabetes increased from 3.0% to 4.1%, while obesity rates rose from 32.7% to 40.9% between 2009 and 2020