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The proportion of patients with body weight loss of 5% at week 24 were 58.1%, 82.5% and 80.3% with mazdutide 3 mg, 4.5 mg and 6 mg, respectively (4.8% with placebo)

This is the same year the FDA approved use of the GLP-1 drug semaglutide, or Wegovy, for weight loss in 12- to 17-year-olds with obesity

Metab Syndr Relat Disord 2007;5:32330

Contudo, como ocorre com outros frmacos desse grupo, o tratamento est associado a efeitos adversos gastrointestinais, como nuseas, vmitos e diarreia, e requer titulao gradual da dose para melhor tolerabilidade

Data availability Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study

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