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They work by inhibiting glucagon secretion, delaying gastric emptying, and suppressing appetite, which helps regulate blood sugar levels and promote weight loss.However, concerns have been raised in recent years over whether these medications reduce weight mainly via muscle mass loss, which could lead to physical frailty or sarcopenia.Led by assistant professor

Trial registration ClinicalTrials.gov NCT05071950

Independent editorial review, not affiliated

GLP-1 medications like Ozempic and Mounjaro can cause fatigue, muscle loss, and balance issues

Sigma noted stronger GLP-1 sales and robust performance across multiple categories

GLP peptides can enhance weight loss results by up to 20%