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If you have a personal or family history of kidney problems, pancreatitis, or diabetic retinopathy, talk to your doctor about these issues

Measurement of outcomes and variables Clinical effectiveness outcomes included ischemic stroke, MI, and their composite

These approaches can be safely continued throughout the preconception period with appropriate professional guidance

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More than half of the cohort continued therapy beyond 6 months (the median duration was 6 months) with only 4 patients extending therapy beyond 12 months

Obesity is also associated with systemic inflammation, increased oxidative stress, and altered metabolism, all of which can negatively impact reproductive tissues