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Only 0.2% of all patients (n=7,660) developed NAION

Growth/differentiation factor-15 (GDF-15) is a stress-induced cytokine expressed in multiple cell types, including cardiomyocytes, adipocytes, and macrophages

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Folate is critical for cell division and DNA repair, while B6 regulates neurotransmitter synthesis

A 2014 study in the Journal of Neuroscience found that activating spinal GLP-1 receptors specifically suppressed pain hypersensitivity via spinal microglia [7]

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