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Most people experience initial appetite suppression within 37 days of their first injection, though the timeline and intensity vary based on individual biology

doi: 10.1158/1078-0432.CCR-13-0458

But there was no increased risk of biliary disease in the cohort looked at, the researchers reported

Conclusions In this large cohort study using nationwide data from three countries, GLP1 receptor agonist use was not associated with a substantially increased risk of thyroid cancer over a mean follow-up of 3.9 years
