glp-1+gip The Effects of Dual GLP-1/GIP Receptor Agonism on Glucagon Secretion—A Review GLP-1 and GIP receptors signal

Stephanie Teotia discuss the following: So many people have lost significant weight with GLP-1 medications, but their neck isn't reflecting that progress

Individual GLP-1 telehealth programs are reviewed with attention to how providers typically operate in practice

Within 48 hours, multiple Indian companies launched cheaper versions

The Cravings Battler: Those fighting a daily battle against uncontrollable cravings, overeating, and endless hunger cues

Reduces appetite aids weight loss Common Drugs (Examples) Exenatide Liraglutide Dulaglutide Semaglutide Lixisenatide Clinical Uses Type 2 Diabetes Mellitus (as monotherapy or combination) Obesity / weight management (especially semaglutide, liraglutide) Cardiovascular benefit: reduces major adverse CV events in T2DM with CVD Administration Subcutaneous injection (daily or weekly depending on formulation) Oral semaglutide available for some patients Adverse Effects Gastrointestinal: nausea, vomiting, diarrhea Risk of pancreatitis (rare but serious) Mild hypoglycemia if combined with sulfonylureas or insulin Injection site reactions Contraindications / Precautions Personal/family history of medullary thyroid carcinoma History of multiple endocrine neoplasia syndrome type 2 (MEN2) Severe gastrointestinal disease (gastroparesis) GLP-1 agonists = incretin mimetics

A new Cleveland Clinic study found those taking GLP-1s were less likely to develop stage IV disease in several cancer types, when compared to patients taking another diabetes medication, DPP-4 inhibitors