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Alterations in mitochondrial functions such as oxidative phosphorylation (OXPHOS) and membrane polarity, which enhance oxidative stress and apoptosis, may precede the development of depressive symptoms [84, 88, 89]
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Case 1 A 47-year-old man presented with progressively worsening blurred vision in OD over three days

Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding

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