eli lily retatrutide Lilly Reports Strong Late-Stage Results for Next-Generation Obesity Drug Retatrutide may become one of
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M., Wahlund, P
GLP-1 RAs reduce gut motility by slowing gastric emptying and altering the migrating motor complex (MMC), increasing the risk of conditions like gastroparesis and bowel obstruction

25 The average proportion of individuals experiencing gastrointestinal side effects in the retatrutide group was similar to that in those receiving dulaglutide 25 though greater than placebo

Participants were randomized to receive placebo or one of several retatrutide dose levels (1 mg, 4 mg, 8 mg, or 12 mg) administered subcutaneously once weekly for 48 weeks