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The association between percentage BMI change and rs10305420 was replication significant, with directionality consistent with that observed in the 23andMe cohort ( P = 0.001

Cardiovascular-related indicators included the incidence of major adverse cardiovascular events (MACE), cardiac function indicators, and the progression of atherosclerotic lesions

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Exploring solutions beyond external tools like surgery, weight loss medications, or dieting

For further detail, the MHRA publishes guidance on the supply of unlicensed medicinal products and on importing medicines, both available on the MHRA website (www.gov.uk/government/organisations/medicines-and-healthcare-products-regulatory-agency)